It's the end of a 30-year family tradition for U.S. Senator Lisa Murkowski.
The Alaskan was defeated in Tuesday's primary by Tea Party conservative Joe Miller in a close race.
Murkowski was chosen in 2002 by her father and governor, Frank Murkowski, who had been senator for 22 years.
Murkowski made the concession speech Tuesday night, a full week after the primary.
Murkowski trailed Miller by 1,668 votes after last week's primary.
Election officials began counting absentee and outstanding ballots Tuesday.