The national quarterfinal game is slated for 2 p.m. (Central Time).
All games will be played at the Regis Soccer and Lacrosse Pitch in Denver.
The Mustangs extended their unbeaten streak to 13 matches with a 1-0 win over Colorado Mines in the second round of the NCAA II Championships Sunday at the MSU Soccer Field.
MSU is now 12-6-3 all time in NCAA postseason play and is looking for its sixth Elite Eight showing as the Mustangs advanced to the national quarterfinals in 2002, 2003, 2007, 2008 and 2010 including trips to the Final Four in 2007 and 2010.
Midwestern is 7-5-2 in playoff matches played outside of Wichita Falls.
NCAA Division II Men's Soccer Playoffs
Regis Soccer and Lacrosse Pitch
All Times Central
Friday, Nov. 22
UC-San Diego vs. Simon Fraser (B.C.), 11 a.m.
Midwestern State vs. Regis (Colo.), 2 p.m.
Sunday, Nov. 24
Friday winners, 2 p.m.